The availability of suitable light sources, ranging from light-emitting diodes (LED) to continuous fluorescent lamps (CFL) and powerful UV lamps (e.g., medium-pressure mercury lamp), furthermore, has driven this development. This renewed interest in utilizing light to bring about chemical reactions is largely fueled by a desire to realize more sustainable approaches for target molecule synthesis, along with significant advances in the field of photoredox catalysis where both transition metals and organic dyes have been exploited. The last decade has witnessed a much-welcomed renaissance and subsequent exploitation of photochemical transformations within the chemistry community. It is hoped that this report provides a valuable update on this important field of synthetic chemistry which may fuel developments in the future. A final section outlines remaining challenges and areas that will benefit from further developments in this fast-moving area. Dedicated sections present the variety of suitable reactor designs and set-ups available a short discussion on the relevance of greener and more sustainable approaches and selected key applications in the area of bioactive structures. To this end we highlight key developments in this field that have contributed to the progress achieved to date. In this focused review article, we wish to evaluate the standing of the field of continuous flow photochemistry with a specific emphasis on the generation of bioactive entities, including natural products, drugs and their precursors. Additionally, the availability of modern continuous flow reactors has enabled widespread applications in view of more streamlined and custom designed flow processes. The last decade has witnessed a remarkable development towards improved and new photochemical transformations in response to greener and more sustainable chemical synthesis needs.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |